Skip to main content
Figure 6 | Molecular Pain

Figure 6

From: Sodium-calcium exchangers in rat trigeminal ganglion neurons

Figure 6

Ca2+-dependence of NCX expressed in TG neurons. (A) Ca2+ influx by NCX in TG activated by substituting Na+-ECS with Li+-ECS while maintaining osmotic strength by replacing NaCl with LiCl. Applied solution-changing protocol for [Na+]o and [Li+]o is shown in upper grey boxes; protocol for [Ca2+]o is shown in lower black boxes. (B) Concentration-response relationship for [Ca2+]o. Data points illustrate F/F0 values as function of applied concentration of extracellular Ca2+. Data points represent mean ± S.E. of number of separate experiments (numbers in parentheses represent number of tested cells). Curve (solid line) on semilogarithmic scale was fitted to Equation 1 described in text. Amax is maximal F/F0 (3.02); Amin is minimal F/F0 (1.30); h is 1.0. Statistically significant differences in F/F0 values recorded between each concentration of 0.02 mM, 0.1 mM, 0.2 mM, 1.0 mM 2.0 mM, 5.0 mM, 10 mM and 0 mM [Ca2+]o are indicated by asterisk: *p<0.05.

Back to article page