Figure 5

Voluntary movements of streptozotocin-induced diabetic mice. (A) Blood glucose levels of mice administered with streptozotocin (STZ) to induce diabetes. Glucose levels were measured at 4 weeks after injecting vehicle or STZ (150 mg/kg i.p.) in mice (n = 7–11). (B) Withdrawal thresholds to von Frey hair filaments of vehicle or STZ treated mice (n = 7–11). (C-D) Voluntary movements in vehicle or STZ treated mice. STZ treated mice showed a significant reduction in the number of rearings (C) and in total distances moved (D) (n = 7–11).