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Figure 5 | Molecular Pain

Figure 5

From: Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine

Figure 5

Effect of tetracaine on ASIC1β and ASIC2a current. A, B. Representative current traces and summary data showing the inhibition of ASIC1β current expressed in Chinese Hamster Ovary cells (CHO) cells by 3 mM tetracaine; (Paired t test, n = 5; ***p < 0.001). C, D. Representative current traces and summary data showing the potentiation of the ASIC2a current in Chinese Hamster Ovary cells (CHO) cells by 10 and 30 mM tetracaine (paired t test, n = 4; *p < 0.05, ***p < 0.001).

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