Figure 6

Inhibition of ASIC3- like current in dorsal root ganglion (DRG) neurons by tetracaine. A, B. Representative current traces and summary data showing a reversible inhibition of the peak and steady state (SS) components of the ASIC3-like current activated at pH 4.5 by 1 mM and 3 mM tetracaine (paired t test, n = 4; *p < 0.05, **p < 0.01, ***p < 0.001). C, D. Representative current traces and summary data showing a reversible inhibition of the amplitude of ASIC3-like current activated at pH 6.0 by 1 mM and 3 mM tetracaine. (paired t test, n = 5; ***p < 0.001).