Figure 5
From: Modulation of TRP channels by resveratrol and other stilbenoids
PME inhibits I CAP but not I AITC in a concentration-dependent manner in DRG neurons. A, B: Representative trace shows ICAP in the absence (A) or presence (B) of PME (30 μM). C: PME inhibited ICAP in a dose-dependent manner. ** p < 0.01 versus control, one-way ANOVA followed by Fisher’s PLSD. Cells were perfused with capsaicin (30 nM) until the current reaching peak in A-C. D: PME showed no inhibitory effect on IAITC (AITC, 100 μM). Numbers in parenthesis indicate cells tested. Calcium-free extracellular solutions were used to prevent TRPV1 desensitization in A-C.