Model | Rank | SNP | CHR | Position | 1st stage | 2nd stage | Final stage | Combined | Genotype | Related gene | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
X 2 | P | X 2 | P | X 2 | P | Q | X 2 | P | Abnormal | Normal | ||||||
Trend | 1 | rs7228266 | 18 | 40874531 | 4.377 | 0.0364 | 6.005 | 0.0143 | 9.102 | 0.0026 | 0.567 | 19.15 | 1.21E-05 | 7/28/16 | 8/92/153 | SETBP1 |
Trend | 2 | rs6537883 | 1 | 110206794 | 5.962 | 0.0146 | 5.917 | 0.015 | 6.385 | 0.0115 | 0.6855 | 18.13 | 2.06E-05 | 2/6/43 | 35/93/121 | CSF1 |
Trend | 3 | rs9474312 | 6 | 52706460 | 5.95 | 0.0147 | 6.026 | 0.0141 | 5.866 | 0.0154 | 0.6855 | 18.03 | 2.18E-05 | 9/24/18 | 11/84/157 | LOC730152 |
Trend | 4 | rs1870761 | 11 | 122356773 | 4.184 | 0.0408 | 7.947 | 0.0048 | 4.011 | 0.0452 | 0.7696 | 15.87 | 6.79E-05 | 0/8/42 | 16/100/134 | BSX |
Trend | 5 | rs139131 | 22 | 42912379 | 7.103 | 0.0077 | 4.071 | 0.0436 | 4.38 | 0.0364 | 0.7696 | 15.6 | 7.81E-05 | 0/7/44 | 10/100/143 | PARVG |
Trend | 6 | rs2295343 | 20 | 3683601 | 4.657 | 0.0309 | 4.81 | 0.0283 | 6.327 | 0.0119 | 0.6855 | 15.11 | 0.000101 | 0/6/45 | 10/93/150 | C20orf27 |
Dominant | 1 | rs6537883 | 1 | 110206794 | 7.505 | 0.0062 | 5.984 | 0.0144 | 8.612 | 0.0033 | 0.4897 | 21.79 | 3.04E-06 | 2/6/43 | 35/93/121 | CSF1 |
Dominant | 2 | rs139131 | 22 | 42912379 | 7.32 | 0.0068 | 4.126 | 0.0422 | 4.264 | 0.0389 | 0.763 | 15.87 | 6.78E-05 | 0/7/44 | 10/100/143 | PARVG |
Dominant | 3 | rs2295343 | 20 | 3683601 | 4.574 | 0.0325 | 5.147 | 0.0233 | 6.631 | 0.01 | 0.5288 | 15.46 | 8.41E-05 | 0/6/45 | 10/93/150 | C20orf27 |
Dominant | 4 | rs10502849 | 18 | 40866089 | 5.286 | 0.0215 | 3.933 | 0.0473 | 6.161 | 0.0131 | 0.5288 | 15.25 | 9.41E-05 | 11/28/11 | 20/101/1 | SETBP1 |
Dominant | 5 | rs707816 | 6 | 13742961 | 4.586 | 0.0322 | 3.933 | 0.0473 | 5.075 | 0.0243 | 0.7257 | 13.08 | 0.000299 | 2/15/34 | 33/121/99 | RANBP9 |
Recessive | 1 | rs2817461 | 6 | 156954704 | 8.06 | 0.0045 | 12.55 | 0.0004 | 12.53 | 0.0004 | 0.0521 | 30.33 | 3.64E-08 | 9/42 | 3/250 | ARID1B |
Recessive | 2 | rs502281 | 6 | 156910640 | 3.991 | 0.0458 | 6.935 | 0.0085 | 16.44 | 5E-05 | 0.0196* | 24.72 | 6.63E-07 | 7/9/35 | 2/71/180 | ARID1B |
Recessive | 3 | rs2063640 | 3 | 103685735 | 6.085 | 0.0136 | 4.932 | 0.0264 | 14.38 | 0.0001 | 0.0291* | 23.07 | 1.56E-06 | 15/11/25 | 17/110/125 | ZPLD1 |
Recessive | 4 | rs13236243 | 7 | 17284837 | 10.43 | 0.0012 | 6.658 | 0.0099 | 4.14 | 0.0419 | 0.7421 | 21.14 | 4.28E-06 | 16/16/19 | 21/121/111 | LOC729939 |
Recessive | 5 | rs1054611 | 12 | 10061428 | 6.1 | 0.0135 | 4.344 | 0.0371 | 11.07 | 0.0009 | 0.0775 | 20.61 | 5.64E-06 | 10/16/25 | 8/84/161 | CLEC12B |
Recessive | 6 | rs6833812 | 4 | 5161041 | 3.991 | 0.0458 | 12.25 | 0.0005 | 5.428 | 0.0198 | 0.4066 | 20.11 | 7.32E-06 | 4/9/38 | 0/57/196 | STK32B |
Recessive | 7 | rs1059513 | 12 | 55775976 | 8.06 | 0.0045 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 20.11 | 7.32E-06 | 4/8/39 | 0/32/221 | STAT6 |
Recessive | 8 | rs1998930 | 6 | 156945948 | 5.157 | 0.0232 | 11.29 | 0.0008 | 6.002 | 0.0143 | 0.4066 | 19.52 | 9.94E-06 | 22/21/8 | 40/130/83 | ARID1B |
Recessive | 9 | rs4235662 | 5 | 84203580 | 7.754 | 0.0054 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 19.42 | 1.05E-05 | 5/18/28 | 1/96/156 | EDIL3 |
Recessive | 10 | rs3804357 | 4 | 102221146 | 5.165 | 0.0231 | 6.551 | 0.0105 | 10.84 | 0.001 | 0.0775 | 19.3 | 1.12E-05 | 8/16/27 | 5/102/144 | PPP3CA |
Recessive | 11 | rs4732828 | 8 | 28050160 | 3.991 | 0.0458 | 5.99 | 0.0144 | 5.791 | 0.0161 | 0.4066 | 15.27 | 9.31E-05 | 3/5/42 | 0/20/232 | ELP3 |
Recessive | 12 | rs4658506 | 1 | 240012540 | 3.991 | 0.0458 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 15.03 | 0.000106 | 3/11/37 | 0/67/186 | WDR64 |
Recessive | 13 | rs2868145 | 19 | 37738954 | 3.991 | 0.0458 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 15.03 | 0.000106 | 3/10/38 | 0/42/211 | PDCD5 |
Recessive | 14 | rs1564492 | 15 | 71720771 | 3.991 | 0.0458 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 15.03 | 0.000106 | 3/10/38 | 0/37/216 | NPTN |
Recessive | 15 | rs1072056 | 5 | 110532014 | 3.991 | 0.0458 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 15.03 | 0.000106 | 3/6/42 | 0/59/194 | WDR36 |
Recessive | 16 | rs10512369 | 9 | 109805180 | 3.991 | 0.0458 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 15.03 | 0.000106 | 3/7/41 | 0/25/228 | LOC392382 |
Recessive | 17 | rs10841907 | 12 | 21942563 | 5.185 | 0.0228 | 5.026 | 0.025 | 4.956 | 0.026 | 0.5072 | 14.95 | 0.00011 | 11/18/21 | 14/104/135 | ABCC9 |
Recessive | 18 | rs9942977 | 9 | 108422182 | 3.895 | 0.0484 | 6.062 | 0.0138 | 5.428 | 0.0198 | 0.4066 | 14.91 | 0.000113 | 3/5/43 | 0/28/223 | LOC644620 |
Recessive | 19 | rs395640 | 21 | 26891730 | 3.991 | 0.0458 | 6.062 | 0.0138 | 6.074 | 0.0137 | 0.4066 | 14.55 | 0.000136 | 4/12/35 | 1/75/177 | CYYR1 |
Recessive | 20 | rs13110230 | 4 | 178153868 | 3.991 | 0.0458 | 6.062 | 0.0138 | 6.074 | 0.0137 | 0.4066 | 14.55 | 0.000136 | 4/9/38 | 1/48/204 | VEGFC |
Recessive | 21 | rs1960997 | 11 | 97149034 | 3.991 | 0.0458 | 4.344 | 0.0371 | 5.675 | 0.0172 | 0.4066 | 11.66 | 0.000638 | 6/19/26 | 5/104/144 | CNTN5 |
Recessive | 22 | rs9535720 | 13 | 51092945 | 3.999 | 0.0455 | 3.907 | 0.0481 | 4.141 | 0.0419 | 0.7421 | 11.61 | 0.000656 | 6/19/26 | 38/140/75 | WDFY2 |