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Figure 1 | Molecular Pain

Figure 1

From: Angiotensin II produces nociceptive behavior through spinal AT1 receptor-mediated p38 mitogen-activated protein kinase activation in mice

Figure 1

Scratching, biting and licking responses induced by i.t.-administered Ang II in mice. (a) Time course of behavioral response induced by Ang II (3 pmol) or Ringer’s solution alone. The ordinate shows the total time of scratching, biting and licking that occurred during each 5 min of measurement. (b) Effects of varying doses of Ang II (1–3 pmol/mouse). The duration of scratching, biting and licking induced by Ang II or Ringer’s solution was determined over a 25 min period starting immediately after i.t. injection. Values represent the means ± S.E.M. for groups of 10 mice. *p < 0.05 compared with Ringer controls.

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