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Figure 5 | Molecular Pain

Figure 5

From: Angiotensin II produces nociceptive behavior through spinal AT1 receptor-mediated p38 mitogen-activated protein kinase activation in mice

Figure 5

Effects of MEK and MAPK inhibitors on i.t. Ang II-induced nociceptive behavior in mice. U0126 (a), SP600125 (b) and SB203580 (c) were co-administered i.t. with Ang II (3 pmol). The duration of scratching, biting and licking induced by Ang II was determined over a 25 min period starting immediately after i.t. injection. Values represent the means ± S.E.M. for groups of 10 mice. **p < 0.01 compared with vehicle (6.8% DMSO) controls and #p < 0.05 compared with Ang II alone. n.s., not significant.

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Molecular Pain

ISSN: 1744-8069

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