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Figure 2 | Molecular Pain

Figure 2

From: Hydrogen sulfide increases excitability through suppression of sustained potassium channel currents of rat trigeminal ganglion neurons

Figure 2

Enhanced excitability by NaHS application. A, representative photographs of DiI-label TG neurons (red, left) and differential interference contrast image (DIC, right). Bar=50 μm. B, NaHS, a donor of H2S at 250 μM was perfused for 3 min. NaHS application significantly depolarized the resting membrane potentials (RP, n=11). C, NaHS application markedly reduced rheobase (n=11). D, NaHS application significantly increased action potential (AP) threshold. Of note is that the effects of NaHS on neuronal excitability were reversible. Values show mean ± S.E.M. *p<0.05 (n=11) versus PRE.

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Molecular Pain

ISSN: 1744-8069

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