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Figure 5 | Molecular Pain

Figure 5

From: 5-HT2CR blockade in the amygdala conveys analgesic efficacy to SSRIs in a rat model of arthritis pain

Figure 5

Drug effects on hindlimb withdrawal thresholds. Reflex thresholds were measured in sham controls (A) and arthritic rats (B) using a calibrated forceps for mechanical compression of the knee joint. Intra-BLA application of SB242084 (10 μM), systemic administration of fluvoxamine (30 mg/kg, i.p), and combined administration of SB242084 and fluvoxamine had no effect on reflex thresholds in control or arthritic rats. Bar histograms show means ± SEM.

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