Results from behavioral tests. Data are for rats 1 d before operation and the same rats operated upon to create unilateral CCI of the sciatic nerve for 3 and 14 d. Progressive development of evoked mechanical allodynia (A) and thermal hyperalgesia (B) was found in the ipsilateral hind paws. No significant changes of mechanical allodynia and thermal hyperalgesia were observed in either contralateral hind paws or forepaws. Data are expressed as relative change of values in comparison to values measured 1 d before operation, such that a value of 1 indicates no change. *Indicates statistically significant difference (p < 0.05) when compared with measurement 1 d before operation.