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Table 1 Staining density for IL-6, IL6R, and gp130 mRNA

From: Dynamic response to peripheral nerve injury detected by in situ hybridization of IL-6 and its receptor mRNAs in the dorsal root ganglia is not strictly correlated with signs of neuropathic pain

Mean density (D ± SD)
Animals Ganglia and time IL-6 IL-6R Gp130
Naïve L-DRGn 0.053 ± 0.006 0.170 ± 0.050 0.320 ± 0.121
C-DRGn 0.042 ± 0.006 0.142 ± 0.042 0.440 ± 0.755
Operated 3D L-DRGi 0.386 ± 0.139* 0.434 ± 0.111* 0.540 ± 0.090
3D L-DRGc 0.427 ± 0.064* 0.405 ± 0.119* 0.450 ± 0.047
3D C-DRGn 0.464 ± 0.069* 0.518 ± 0.119* 0.490 ± 0.394
14D L-DRGi 0.536 ± 0.070* 0.273 ± 0.065* 0.470 ± 0.192
14D L-DRGc 0.419 ± 0.132* 0.165 ± 0.030 0.250 ± 0.182
14D C-DRGn 0.332 ± 0.079* 0.201 ± 0.046 0.440 ± 0.154
Sham-operated 3D L-DRGi 0.045 ± 0.006 0.241 ± 0.053 0.370 ± 0.276
3D L-DRGc 0.062 ± 0.006 0.232 ± 0.030 0.270 ± 0.089
3D C-DRGn 0.056 ± 0.006 0.207 ± 0.062 0.320 ± 0.459
14D L-DRGi 0.075 ± 0.010 0.208 ± 0.033 0.290 ± 0.544
14D L-DRGc 0.074 ± 0.007 0.159 ± 0.015 0.340 ± 0.058
  14D C-DRGn 0.085 ± 0.005 0.210 ± 0.040 0.490 ± 0.309
  1. * Statistical significance (p < 0.05) when compared with naïve DRG.
  2. Results of staining density for mRNA in lumbar ipsilateral (L-DRGi), lumbar contralateral (L-DRGc), and cervical (C-DRGn) dorsal root ganglia removed from naïve (Naïve), CCI- and sham-operated rats for 3 and 14 d of survival (3D, 14D).