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Figure 4 | Molecular Pain

Figure 4

From: Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat

Figure 4

Effects of intra-VL PAG microinjections of vehicle (0.05% DMSO in ACSF) or MMPIP (5 μg/0.2 μl) on tail flick-evoked burst of firing (A) and onset of the burst (B) of the ON cells or tail flick-evoked pause (C) and onset of the pause (D) of the OFF cells in sham and SNI rats 14 days after surgery. Each histogram represents the mean ± S.E.M of 6–7 neurons of different treated groups of rats. * indicates significant differences vs pretreatment values. P values < 0.05 were considered statistically significant.

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Molecular Pain

ISSN: 1744-8069

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