Figure 5
From: Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury
Effect of injury on σ1 receptor (σ1R) expression in sensory neurons identified by IB4 staining. (A) Staining of σ1R was distributed within cytoplasmic areas of all IB4 co-expressing neurons. σ1R immunofluorescence intensity was decreased in spinal nerve ligation (SNL) 5th lumbar (L5) neurons compared with Control. (B) Summary data showed decrease of intensity of σ1R staining in IB4-positive SNL L5 neurons. Mean ± SEM; number in bars represents the sample size; ***p < 0.001.