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Figure 4 | Molecular Pain

Figure 4

From: Activation of mammalian target of rapamycin mediates rat pain-related responses induced by BmK I, a sodium channel-specific modulator

Figure 4

BmK I-induced changes in spinal levels of p-mTOR, p-4E-BP1 and p-p70 S6K assessed by Western blot. (A) &(F), representative western blots showing levels of p-mTOR, p-4E-BP, p-p70 S6K, total mTOR and β-actin in both ipsi- (A) and contralateral (B) side of the spinal cord. (B-E) &(G-J), histograms represent the mean levels with respect to each control group at different time points after intraplantar BmK I injection. The data are presented as mean ± S.E.M. of three rats per group. *p<0.05, **p<0.01, ***p<0.001, compared with control group by One-way ANOVA, followed by Bonferroni's post hoc test.

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