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Figure 4 | Molecular Pain

Figure 4

From: Novel ω-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration

Figure 4

Time-course and dose-dependence of reversal of allodynia by systemic ω-conotoxins. A-C. Systemic ω-conotoxins partially reverse CFA-induced incapacitance. Effects of CVID, CVIE and CVIF respectively at doses of 0.02, 0.2 and 2 mg/kg on allodynia following CFA injection. D. Area under the curve measurements corrected for baseline with vehicle show that CVID and CVIE were the most effective at reversing mechanical alldoynia, with CVID reaching a ceiling effect at 0.2 mg/kg which was not seen with CVIE.

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Molecular Pain

ISSN: 1744-8069

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