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Figure 2 | Molecular Pain

Figure 2

From: Chemokine expression in peripheral tissues from the Monosodium Iodoacetate model of chronic joint pain

Figure 2

Day 3: Distribution of inflammatory mediator expression in each tissue as ranked by FC. (A) The distribution profile of mediator expression in each tissue at day 3 in the MIA model. The data points show the mean FC for each individual transcript. These values are ranked in order, starting from those most down-regulated (compared to control), to those most up-regulated. Adjacent data points in different tissues do not necessarily correspond to the same gene. The blue shaded box represents an area of +/-2 ≤ FC. X-axis is on a log2 scale. Data are displayed as the mean FC, FC = MIA/Control, n = 92. (B) The percentage of genes > 2 FC up-regulated in the each tissue. As shown, the greatest percentage of genes was up-regulated in the cartilage (42.5%) as compared to the subchondral bone (16.1%) and fat pad (10.8%).

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Molecular Pain

ISSN: 1744-8069

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