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Figure 4 | Molecular Pain

Figure 4

From: N-type voltage gated calcium channels mediate excitatory synaptic transmission in the anterior cingulate cortex of adult mice

Figure 4

Role of other VGCCs in ACC excitatory synaptic transmission in the deep layer. A, Averaged data of 6 channels in the deep layer in one slice, showing the effect of applying ω-Aga IVA (1 μM) for 20 min. B, Pooled data of 5 mice (96.9 ± 1.4% of baseline, n = 5 slices/5 mice). C, Averaged data of 8 channels in the deep layer in one slice, showing the effect of applying SNX-482 (0.5 μM) for 20 min. D, Pooled data of 6 mice (98.0 ± 0.2% of baseline, n = 6 slices/6 mice). E, Averaged data of 6 channels in the deep layer in one slice, showing the effect of applying NiCl2 (100 μM) for 20 min. F, Pooled data of 7 mice (97.7 ± 1.3% of baseline, n = 7 slices/7 mice). G, Averaged data of 7 channels in the deep layer in one slice, showing the effect of applying nimodipine (10 μM) for 20 min. H, Pooled data of 5 mice (98.0 ± 1.9% of baseline, n = 5 slices/5 mice). All drugs infused had no effect on synaptic transmission in the deep layer of the ACC. The horizontal bars indicate the period of drug application. Error bars represent SEM.

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