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Figure 3 | Molecular Pain

Figure 3

From: Mechanical sensitization of cutaneous sensory fibers in the spared nerve injury mouse model

Figure 3

Distribution of cutaneous fiber types in SNI mice. Since SNI mice fired significantly more action potentials per second across all forces, we compared the percent distribution of each fiber type across treatment groups. A) There was not a significant difference in percent fiber distribution in SNI mice compared to sham or naïve animals (p>0.05). B) SNI mice have a similar distribution of AM and DH fibers as sham and naïve animals (p>0.05). C) There was an overall difference in the distribution of Aβ fibers among SNI, sham and naïve mice (*p<0.05). There was a decrease in the proportion of slowly adapting (SA) Abeta fibers in SNI mice compared to sham (*p<0.5), although no difference was observed between SNI and naive animals (p>0.5). Distribution data was analyzed using a Chi-square analysis and Fisher’s exact post hoc tests.

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