Analgesic tolerance of opioid agonists in mutant mu-opioid receptors expressed in sensory neurons following intrathecal plasmid gene delivery

Table 1 HA-labeled hMOR and hMOR-T expressed in different sized DRG neurons

	Small cell	Medium cell	Large cell	Total†
	**d < 25 μm***	*25 < d < 35 μm*	*d > 35 μm*
Saline	0	0	0	0
hMOR	9.71 ± 0.66	18.22 ± 1.83	1.82 ± 0.24	29.75
hMOR-T	11.08 ± 0.17	19.14 ± 1.86	0.45 ± 0.45	30.67

Total number of cells counted as 100%; all values are HA-labeled cells expressed as % of counted cells. Values are means ± SE; 3 rats in each rat group.
*d: cell diameter. †Total: total percentage, including small, medium and large cells, of HA-labeled cells.
There were no significant differences between hMOR and hMOR groups in all sizes of DRG neurons.

ISSN: 1744-8069