Figure 5

Inter-regional rCBF in sham rats was analyzed by assessing correlations. Twenty-two ROIs that showed significant increases in radioactivity counts in sham rats were included into the correlation analysis. A. Inter-regional correlation matrix for the sham group. The matrix is symmetrical across the diagonal line from the lower left to the upper right. Notice the strong positive connections among cortical ROIs, including the cortex (IL, PrL, Cg1-1, Cg1-2, S1-3, AID, and AIV) and thalamus (MD, VL, and VM). The connections among the VB, hypothalamus (LH and VMH), Amygdala (Amygdala-1 and Amygdala-2), and PAG were weakly positive with this corticostriatal cluster. B. Inter-regional correlations of rCBF of the mPFC-amygdala pathway in the sham group. The vertices (colored dots) represent ROIs of different brain areas. The connectivity map showed connections between vertices with significant correlations. C. Graphical representation of the inter-regional correlations of rCBF of the MT-ACC pathway and STT in the sham group.