Figure 1

MeCP2 overexpression attenuates both mechanical and thermal pain sensitivity. A, Comparison of paw withdrawal threshold to mechanical stimulation between WT mice and MeCP2 overexpression mice (OE). 7 mice were tested in each group. B, Comparison of pain sensitivity to thermal stimulation between WT mice and MeCP2 overexpression mice (OE). n = 9 for WT and OE respectively. All values are represented as means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001.