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Figure 3 | Molecular Pain

Figure 3

From: Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain

Figure 3

Lack of ectopic sprouting from labeled trigeminal Aβ afferents at 14 and 22 days after ION transection. (A) Schematic of experimental procedure for results shown in B-D. (B) Representative spinal caudalis (SpC) section from Pv-CreER; Ai14 transgenic mice 14 days after ION injury on the left side, and sham operation on the right side. Red: labeled Aβ axon collaterals; Green: IB4-488 staining marked lamina II; Blue: DAPI. (C-D) High magnification images of the boxed areas in B. (E) Schematic of experimental procedure for results shown in F-H. (F) Representative SpC section from Pv-CreER; Ai14 transgenic mice 22 days after ION injury on the left side. (G-H) High magnification images of boxed areas in F. Scale bar: 100 μm.

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