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Table 1 Incidence of chronic dry eye symptoms after refractive surgery

From: Chronic dry eye symptoms after LASIK: parallels and lessons to be learned from other persistent post-operative pain disorders

Study Procedure N Design Definition Incidence
Denoyer 2014 [18] LASIK 60 Prospective series Use of eye drops at 6 months 43%
De Paiva 2006 [19] LASIK 35 Prospective randomized (nasal vs. superior hinge) Fluorescein staining score of 3 or more at 6 months 36.4% (overall)
Shoja 2007 [14] LASIK 95 Retrospective series Subjective symptoms at 6 months 20%
Donnenfeld 2003 [20] LASIK 52 Prospective randomized (nasal vs. superior hinge) Patients reporting eyes drier than before LASIK at 6 months 31% (overall)
Tuisku 2007 [13] LASIK 20 cases Retrospective case-control Subjective symptoms at 2 - 5
years
55%
Hovanesian 2001 [16] LASIK and PRK 781 Mailed questionnaire Subjective symptoms at 6 months or more 44%
  1. LASIK = laser in-situ keratomileusis, PRK = photorefractive keratectomy.