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Table 2 Select neurochemical markers of the cornea, adapted from Shaheen et al., 2014 [24]

From: Chronic dry eye symptoms after LASIK: parallels and lessons to be learned from other persistent post-operative pain disorders

Nerve fiber type Associated markers
Somatosensory (mechanical) NF-200
Somatosensory (nociceptive)  
  Peptidergic CGRP
SP
PACAP
Galanin
  Non-peptidergic FRAP
Autonomic  
  Sympathetic NE
5-HT
NPY
  Parasympathetic Ach
VIP
NPY
Galanin
  1. NF-200 = neurofilament-200 kDa, CGRP = calcitonin gene-related peptide, SP = substance P, PACAP = pituitary adenylate cyclase activating peptide, FRAP = fluoride-resistant acid phosphatase, NE = norepinephrine, 5-HT = serotonin, NPY = neuropeptide Y, Ach = acetylcholine, VIP = vasoactive intestinal peptide.