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Figure 2 | Molecular Pain

Figure 2

From: Minocycline does not affect long-term potentiation in the anterior cingulate cortex of normal adult mice

Figure 2

Spatial analysis of post-LTP distribution in the ACC. A and B: polygonal diagram of the channels that are activated in the baseline (blue, A) and that undergo post-LTP (red, B) in 5 slices from 5 mice. Vertical lines denote the layers in the ACC slice. Overlapped blue regions denote frequently activated channels, while overlapped red regions indicate the channels that are most likely to undergo post-LTP. Most, although not all, of the activated channels exhibited post-LTP after TBS. C and D: spatial analysis of the effects of minocycline on post-LTP distribution maps in the ACC. Shown are the polygonal graphs of activated (blue, C) and post-LTP-occurring (red, D) channels among the cingulate network when TBS is applied in the presence of minocycline (nā€‰=ā€‰7 slices/7c mice). Minocycline does not affect the number of post-LTP-showing channels in the ACC.

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