Spatial analysis of pre-LTP distribution in the ACC. A and B: polygonal diagram of the channels that are activated in the baseline (blue, A) and that undergo pre-LTP (red, B) in 7 slices from 7 mice. Vertical lines denote the layers in the ACC slice. C and D: spatial analysis of the effects of minocycline on pre-LTP distribution maps in the ACC. Shown are the polygonal graphs of activated (blue, C) and pre-LTP-occurring (red, D) channels among the cingulate network when LFS + ATPA is applied in the presence of minocycline (n = 5 slices/5 mice). Spatial distribution of pre-LTP-showing channels is not significantly altered by minocycline.