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Fig. 5 | Molecular Pain

Fig. 5

From: Pain perception in acute model mice of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Fig. 5

Quantitative analysis of astroglial and microglial activation to MPTP treatment in the spinal cord. a Comparison of GFAP-immunopositive astrocytes in the dorsal horn of the lumbar spinal cord between saline- and MPTP-treated mice (scale bars = 200 μm). b Saline- and MPTP-treated mice showed no difference in the number of astrocytes in the spinal cord (n = 4 per group, unpaired t-test). c Comparison of Iba1-immunopositive microglia in the dorsal and ventral horn of the lumbar spinal cord between saline- and MPTP-treated mice (scale bars = 200 μm). d Saline- and MPTP-treated mice showed no difference in the number of microglial cells in the spinal cord (n = 4 per group, unpaired t-test). e Comparison of TH-immunopositive neurons (red arrows) in the ventral horn of the lumbar spinal cord between saline- and MPTP-treated mice (scale bars = 200 μm). f Saline- and MPTP-treated mice showed no difference in the number of TH-positive neurons in the spinal cord (n = 4 per group, unpaired t-test)

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Molecular Pain

ISSN: 1744-8069

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