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Table 1 Blood glucose level and body weight of experimental rats

From: Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons

Group Old rats, T-current measurementsa Old rats, Na-current measurementsb 2-3 months old ratsc
  Control Diabetic 9-13 weeks Control Diabetic 9-13 weeks Control Diabetic 6-7 weeks
Hypoalgesic Hyperalgesic
Body weight, g 325 + 25 212 + 20d 323 + 12 213 + 14d 153 + 4 128 + 11e 125 + 8e
Blood glucose level, mM 4.5 + 0.3 27 + 2f 4.4 + 0.2 28 + 2f 4.3 + 0.3 27 + 2g 26 + 2g
n 4 4 3 3 3 3 3
  1. aAnimals (8 months old) were used to measure T-type current and excitability parameters
  2. bAnimals (8 months old) were used to measure Na+ current
  3. cAnimals were used to measure T-type current
  4. dANOVA one way test, p < 0.01
  5. eThere was no significant difference between the group of diabetic hypoalgesic or hyperalgesic and control rats (p > 0.08, ANOVA one way test)
  6. fStudent’s t-test: p < 0.001 for each control and corresponding diabetic group
  7. gStudent’s t-test with α level adjusted with Bonferroni’s procedure: p < 0.005 when diabetic hypoalgesic and hyperalgesic groups were compared with the same control group
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Molecular Pain

ISSN: 1744-8069

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