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Figure 5 | Molecular Pain

Figure 5

From: PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias

Figure 5

LY294002 treatment following QUIS-induced spinal injury prevents the development of at-level dysesthesias 14 days after injury. a Photograph of overgrooming lesion from QUIS vehicle treated animal primarily observed on at-level ipsilateral dermatome, class II bilateral groomer. b The incidence of overgrooming behavior was reduced from 42% (5/12) in animals treated with DMSO to 0% in animals treated with LY following SCI (0/11; p = 0.03).

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Molecular Pain

ISSN: 1744-8069

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