Intrathecal injection of non-selective and selective CaCCs inhibitors reduces thermal hyperalgesia. Time-course of the antihyperalgesic effect of NFA (300 μg), T16Ainh-A01 (10 μg) and CaCCinh-A01 (10 μg) in rats subjected to L5/L6 spinal nerve injury compared to naïve, sham and vehicle groups. Withdrawal latency was assessed 14 days after spinal nerve injury. Data are presented as the mean ± SEM for six animals determined by the mean of three trials for each rat at each time. Note that CaCCs inhibitors increased withdrawal latency. *Significantly different from the vehicle group (p < 0.05), as determined by repeated measures two-way ANOVA followed by the Bonferroni test.