Figure 9From: Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in ratsEffect of CaCCs inhibitors on the CAP of naïve and neuropathic rats. Upper panels examples of the CAP recorded in absence (control, black trace) and in presence of T16Ainh-A01 [20 μM] (red trace) recorded from naïve (a) and neuropathic (c) rats. The bar charts below of traces show the comparison of normalized area under the C component of the CAP between the naïve and T16Ainh-A01 groups. Note that T16Ainh-A01 diminished the compound action potential in neuropathic, but not in naïve, rats. Lower panels examples of CAP recorded in absence (control, black trace) and in presence of CaCCinh-A01 [20 μM] (red traces) recorded from naïve (b) and neuropathic (d) rats. The bar charts below of traces compare the normalized area under the C component of the CAP between the control and CaCCinh-A01 groups. Note that CaCCinh-A01 decreased the CAP size in neuropathic, but not in naïve, rats. *Significantly different from the neuropathic group (p < 0.05), as determined by the Student t test.Back to article page