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Table 1 Effective doses of the non-selective and selective CaCCs inhibitors in spinal nerve injury-induced tactile allodynia. Drugs were administered as a post-treatment. Data were collected from the ipsilateral paw 14 days after spinal nerve ligation. Data are presented as the mean (n = 6) ± SEM.

From: Role of anoctamin-1 and bestrophin-1 in spinal nerve ligation-induced neuropathic pain in rats

Inhibitor

ED50 (µg)

NPPB

183.2 ± 4.9

9AC

132 ± 46.7

NFA

109.9 ± 3.8

T16Ainh-A01

1.8 ± 0.3

CaCCinh-A01

0.4 ± 0.1