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Figure 4 | Molecular Pain

Figure 4

From: Function and postnatal changes of dural afferent fibers expressing TRPM8 channels

Figure 4

The axonal branching of CGRP-positive fibers is stable in P2 and adult mouse dura. a Representative images of axons containing CGRP-ir in the dura of P2 and adult wild-type mice. Each image contains one fiber. Arrows indicate individual branch points on the fiber. b The average number of CGRP-positive fibers per mm2 of P2 and adult mouse dura (n = 10 and 6 mice, respectively). c The percentage of CGRP-positive fibers without branch points in P2 and adult mouse dura (same mice as in b, p = 0.41, two-tailed t-test). d The average number of branch points per EGFP- or CGRP-positive fiber in P2 and adult mouse dura (same mice as in Figures 3e and 4b). *p < 0.05, ***p < 0.001, two-way ANOVA with post hoc Bonferroni test.

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