Axonal transport of GIRK1-LI. A GIRK1-LI is observed in many PGP9.5+ fibers in intact sciatic nerve. B After a 10-h nerve ligation, a strong accumulation of GIRK1-LI is seen on both proximal and distal side (arrowheads). C A few GIRK1+ and PGP9.5+ fibers (arrowheads) are observed in the epidermis layer of glabrous skin in rat hind paw. D Twenty-one days after unilateral lumbar dorsal rhizotomy, a reduction of GIRK1-LI is seen within region 2 (arrowheads), but not in region 1 (arrows), as compared with the contralateral side. A dramatic reduction of CGRP-LI is seen ipsilaterally. Scale bars indicate 500 μm (B), 200 μm (A, C, low magnification; D), 50 μm (C, high magnification).