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Figure 4 | Molecular Pain

Figure 4

From: G protein-gated inwardly rectifying potassium channel subunits 1 and 2 are down-regulated in rat dorsal root ganglion neurons and spinal cord after peripheral axotomy

Figure 4

GIRK1 and -2 co-exist with galanin (Gal) or nNOS in ipsilateral DRG neurons after unilateral axotomy. A–F Double staining shows that GIRK1 (A, D) co-exists with Gal (B, C) and nNOS (E, F). Arrowheads indicate co-existence (yellow). G–L Double staining shows that GIRK2 (G, J) neither co-exists with Gal (H, I) nor nNOS (K, L). M Quantification analysis shows the percentage of GIRK1+ and -2+ NPs that co-express Gal or nNOS (M1), and conversely the percentage of Gal+ and nNOS+ NPs that co-express GIRK1 or -2 (M2). Scale bar indicates 40 μm (A–L, valid for all).

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