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Table 3 DE lncRNAs and their neighboring or overlapping DE mRNAs

From: Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain

LncRNAs Relationship mRNAs Function prediction of DE lncRNAs with related mRNAs
Sequence name Fold change Regulation GeneSymbol Fold change Regulation Molecular Function Pathway
ENSMUST00000160110 3.9130898 Down Antisense overlap Phtf1 2.1720073 Down GO:0003677 DNA binding  
AK136749 2.089502 Up Antisense overlap Asap2 8.8652115 Up   
ENSMUST00000121460 11.624642 Up Antisense overlap Mup2 16.324926 Up GO:0005215 transporter activity
GO:0005550 pheromone binding
mouselincRNA1303+ 2.959626 Up Intergenic Vmn1r54 2.5373068 Up   
MM9LINCRNAEXON12110+ 9.611986 Up Intergenic Apoa2 5.3063893 Up GO:0005319 lipid transporter activity
GO:0008035 high-density lipoprotein binding
GO:0017127 cholesterol transporter activity
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0055102 lipase inhibitor activity
GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity
PPAR signaling pathway
MM9LINCRNAEXON11813− 2.2022471 Up Intergenic Ngfr 2.3073637 Up GO:0005030 neurotrophin receptor activity
GO:0048406 nerve growth factor binding
Neurodegenerative disorders
Cytokine–cytokine receptor interaction
C75950 2.3177905 Up Intergenic Gm5136 2.2296717 Down   
mouselincRNA1231− 2.3548565 Up Intergenic Hvcn1 2.0545347 Up GO:0005244 voltage-gated ion channel activity
GO:0030171 voltage-gated proton channel activity
ENSMUST00000133243 2.2177694 Up Intergenic Uspl1 2.747246 Up GO:0004221 ubiquitin thiolesterase activity  
MM9LINCRNAEXON11661+ 20.514269 Up Intergenic Asap2 8.8652115 Up   
humanlincRNA1070+ 6.5686955 Up Intergenic Vax2 17.30259 Up GO:0003700 transcription factor activity  
humanlincRNA2255− 6.4199057 Up Intergenic Trhr 2.1457152 Down   
mouselincRNA1631+ 2.131738 Up Intergenic Klhl15 2.0060081 Up GO:0005515 protein binding  
humanlincRNA1443− 4.366208 Up Intergenic Igsf10 7.495438 Up GO:0005021 vascular endothelial growth factor receptor activity
GO:0005515 protein binding
GO:0005524 ATP binding
MM9LINCRNAEXON12110+ 9.611986 Up Intergenic Dedd 2.2202826 Down GO:0003677 DNA binding
GO:0005515 protein binding
MM9LINCRNAEXON10576− 5.209898 Up Intergenic Cxcl9 5.6018896 Up GO:0008009 chemokine activity Cytokine–cytokine receptor interaction
Toll-like receptor signaling pathway
MM9LINCRNAEXON11308+ 3.7596319 Up Intergenic Zfp654 2.1100945 Down GO:0003677 DNA binding
GO:0008270 zinc ion binding
BM248967 6.0079184 Up Intergenic Dgkk 3.3316648 Up GO:0004143 diacylglycerol kinase activity  
MM9LINCRNAEXON11616+ 2.5639145 Up Intergenic Hexb 2.0003252 Up GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004563 beta-N-acetylhexosaminidase activity
GO:0042803 protein homodimerization activity
GO:0043169 cation binding
GO:0046982 protein heterodimerization activity
N-Glycan degradation
Aminosugars metabolism
Glycosaminoglycan degradation
Glycosphingolipid biosynthesis—globoseries
Glycosphingolipid biosynthesis—ganglioseries
Glycan structures—degradation
uc008iab.1 2.1543121 Down Intergenic Fam160b1 2.5731633 Up   
MM9LINCRNAEXON12066− 4.066157 Down Intergenic Tnnt2 3.0204759 Down GO:0005200 structural constituent of cytoskeleton  
MM9LINCRNAEXON10576− 5.209898 Up Intergenic Cxcl11 2.7319772 Up GO:0008009 chemokine activity Cytokine–cytokine receptor interaction
Toll-like receptor signaling pathway
MM9LINCRNAEXON10576− 5.209898 Up Intergenic Cxcl10 6.9877048 Up GO:0008009 chemokine activity Cytokine–cytokine receptor interaction
Toll-like receptor signaling pathway
AK054438 2.3012707 Up Intergenic Ifi202b 9.431554 Up GO:0005515 protein binding  
MM9LINCRNAEXON10268− 6.8239675 Up Intergenic Irf8 2.335659 Up GO:0003700 transcription factor activity  
MM9LINCRNAEXON11735+ 2.4868224 Down Intergenic Ppp2r5c 2.1656942 Down GO:0008601 protein phosphatase type 2A regulator activity  
DV650983 2.0293975 Down Intergenic Olfr1416 2.2257524 Up GO:0004984 olfactory receptor activity Olfactory transduction
MM9LINCRNAEXON11795+ 2.5727692 Down Intergenic Cd68 2.6843183 Up   
MM9LINCRNAEXON11793+ 2.671865 Up Intergenic Cd68 2.6843183 Up   
ENSMUST00000120184 2.5531633 Down Sense overlap Amy2b 2.4439986 Down   
uc007vpp.1 2.1796808 Down Sense overlap Trhr 2.1457152 Down GO:0004872 receptor activity
GO:0004997 thyrotropin-releasing hormone receptor activity
Calcium signaling pathway
Neuroactive ligand–receptor interaction
uc009pmr.1 3.20246 Down Sense overlap Elmod1 2.2530112 Down   
uc007cua.1 6.378551 Down Sense overlap Tnnt2 3.0204759 Down   
ENSMUST00000040306 4.188862 Down Sense overlap H2-Ea-ps 3.2939498 Down   
uc008uzw.1 2.2820547 Up Sense overlap Laptm5 2.1142242 Up   
ENSMUST00000117412 2.5116289 Up Sense overlap Gm10147 2.2881203 Up   
ENSMUST00000119882 3.1487308 Up Sense overlap Gm10486 2.4736855 Up   
ENSMUST00000119882 3.1487308 Up Sense overlap Gm14819 3.018787 Up   
uc008tbm.1 10.098583 Up Sense overlap Mup17 21.82689 Up