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Table 3 DE lncRNAs and their neighboring or overlapping DE mRNAs

From: Identification of lncRNA expression profile in the spinal cord of mice following spinal nerve ligation-induced neuropathic pain

LncRNAs

Relationship

mRNAs

Function prediction of DE lncRNAs with related mRNAs

Sequence name

Fold change

Regulation

GeneSymbol

Fold change

Regulation

Molecular Function

Pathway

ENSMUST00000160110

3.9130898

Down

Antisense overlap

Phtf1

2.1720073

Down

GO:0003677 DNA binding

 

AK136749

2.089502

Up

Antisense overlap

Asap2

8.8652115

Up

  

ENSMUST00000121460

11.624642

Up

Antisense overlap

Mup2

16.324926

Up

GO:0005215 transporter activity

GO:0005550 pheromone binding

 

mouselincRNA1303+

2.959626

Up

Intergenic

Vmn1r54

2.5373068

Up

  

MM9LINCRNAEXON12110+

9.611986

Up

Intergenic

Apoa2

5.3063893

Up

GO:0005319 lipid transporter activity

GO:0008035 high-density lipoprotein binding

GO:0017127 cholesterol transporter activity

GO:0042803 protein homodimerization activity

GO:0046982 protein heterodimerization activity

GO:0055102 lipase inhibitor activity

GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity

PPAR signaling pathway

MM9LINCRNAEXON11813−

2.2022471

Up

Intergenic

Ngfr

2.3073637

Up

GO:0005030 neurotrophin receptor activity

GO:0048406 nerve growth factor binding

Neurodegenerative disorders

Cytokine–cytokine receptor interaction

C75950

2.3177905

Up

Intergenic

Gm5136

2.2296717

Down

  

mouselincRNA1231−

2.3548565

Up

Intergenic

Hvcn1

2.0545347

Up

GO:0005244 voltage-gated ion channel activity

GO:0030171 voltage-gated proton channel activity

 

ENSMUST00000133243

2.2177694

Up

Intergenic

Uspl1

2.747246

Up

GO:0004221 ubiquitin thiolesterase activity

 

MM9LINCRNAEXON11661+

20.514269

Up

Intergenic

Asap2

8.8652115

Up

  

humanlincRNA1070+

6.5686955

Up

Intergenic

Vax2

17.30259

Up

GO:0003700 transcription factor activity

 

humanlincRNA2255−

6.4199057

Up

Intergenic

Trhr

2.1457152

Down

  

mouselincRNA1631+

2.131738

Up

Intergenic

Klhl15

2.0060081

Up

GO:0005515 protein binding

 

humanlincRNA1443−

4.366208

Up

Intergenic

Igsf10

7.495438

Up

GO:0005021 vascular endothelial growth factor receptor activity

GO:0005515 protein binding

GO:0005524 ATP binding

 

MM9LINCRNAEXON12110+

9.611986

Up

Intergenic

Dedd

2.2202826

Down

GO:0003677 DNA binding

GO:0005515 protein binding

 

MM9LINCRNAEXON10576−

5.209898

Up

Intergenic

Cxcl9

5.6018896

Up

GO:0008009 chemokine activity

Cytokine–cytokine receptor interaction

Toll-like receptor signaling pathway

MM9LINCRNAEXON11308+

3.7596319

Up

Intergenic

Zfp654

2.1100945

Down

GO:0003677 DNA binding

GO:0008270 zinc ion binding

 

BM248967

6.0079184

Up

Intergenic

Dgkk

3.3316648

Up

GO:0004143 diacylglycerol kinase activity

 

MM9LINCRNAEXON11616+

2.5639145

Up

Intergenic

Hexb

2.0003252

Up

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

GO:0004563 beta-N-acetylhexosaminidase activity

GO:0042803 protein homodimerization activity

GO:0043169 cation binding

GO:0046982 protein heterodimerization activity

N-Glycan degradation

Aminosugars metabolism

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis—globoseries

Glycosphingolipid biosynthesis—ganglioseries

Glycan structures—degradation

uc008iab.1

2.1543121

Down

Intergenic

Fam160b1

2.5731633

Up

  

MM9LINCRNAEXON12066−

4.066157

Down

Intergenic

Tnnt2

3.0204759

Down

GO:0005200 structural constituent of cytoskeleton

 

MM9LINCRNAEXON10576−

5.209898

Up

Intergenic

Cxcl11

2.7319772

Up

GO:0008009 chemokine activity

Cytokine–cytokine receptor interaction

Toll-like receptor signaling pathway

MM9LINCRNAEXON10576−

5.209898

Up

Intergenic

Cxcl10

6.9877048

Up

GO:0008009 chemokine activity

Cytokine–cytokine receptor interaction

Toll-like receptor signaling pathway

AK054438

2.3012707

Up

Intergenic

Ifi202b

9.431554

Up

GO:0005515 protein binding

 

MM9LINCRNAEXON10268−

6.8239675

Up

Intergenic

Irf8

2.335659

Up

GO:0003700 transcription factor activity

 

MM9LINCRNAEXON11735+

2.4868224

Down

Intergenic

Ppp2r5c

2.1656942

Down

GO:0008601 protein phosphatase type 2A regulator activity

 

DV650983

2.0293975

Down

Intergenic

Olfr1416

2.2257524

Up

GO:0004984 olfactory receptor activity

Olfactory transduction

MM9LINCRNAEXON11795+

2.5727692

Down

Intergenic

Cd68

2.6843183

Up

  

MM9LINCRNAEXON11793+

2.671865

Up

Intergenic

Cd68

2.6843183

Up

  

ENSMUST00000120184

2.5531633

Down

Sense overlap

Amy2b

2.4439986

Down

  

uc007vpp.1

2.1796808

Down

Sense overlap

Trhr

2.1457152

Down

GO:0004872 receptor activity

GO:0004997 thyrotropin-releasing hormone receptor activity

Calcium signaling pathway

Neuroactive ligand–receptor interaction

uc009pmr.1

3.20246

Down

Sense overlap

Elmod1

2.2530112

Down

  

uc007cua.1

6.378551

Down

Sense overlap

Tnnt2

3.0204759

Down

  

ENSMUST00000040306

4.188862

Down

Sense overlap

H2-Ea-ps

3.2939498

Down

  

uc008uzw.1

2.2820547

Up

Sense overlap

Laptm5

2.1142242

Up

  

ENSMUST00000117412

2.5116289

Up

Sense overlap

Gm10147

2.2881203

Up

  

ENSMUST00000119882

3.1487308

Up

Sense overlap

Gm10486

2.4736855

Up

  

ENSMUST00000119882

3.1487308

Up

Sense overlap

Gm14819

3.018787

Up

  

uc008tbm.1

10.098583

Up

Sense overlap

Mup17

21.82689

Up

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