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Fig. 6 | Molecular Pain

Fig. 6

From: KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia

Fig. 6

Alleviation by retigabine of orofacial cold hyperalgesia in infraorbital nerve chronic constrictive injury model. Bar graph shows total contact time of orofacial operant tests for infraorbital nerve chronic constrictive injury (ION-CCI) animals under the following conditions: 24, 12, 12°C with vehicle injection, 12°C with retigabine treatment at the doses of 0.19, 0.56, and 1.67 mg/kg. Retigabine was administrated intraperitoneal to the animals. Data represent Mean ± SEM, *P < 0.05; **P < 0.01.

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Molecular Pain

ISSN: 1744-8069

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