The effect of koumine on 3α-hydroxysteroid oxidoreductase mRNA expression in the spinal cord of sciatic nerve chronic constriction injury rats. The 3α-hydroxysteroid oxidoreductase (3α-HSOR) mRNA level is expressed as the ratio of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA in the spinal cord (SC) of naïve, sham-operated, sciatic nerve chronic constriction injury (CCI), or koumine-treated rats. The data are presented as the mean ± SEM (n = 6 per group) and were analyzed by two-way ANOVA followed by Bonferroni post hoc test at each time point. ##
P < 0.01 vs. the sham group; *P < 0.05 vs. the CCI group.