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Fig. 2 | Molecular Pain

Fig. 2

From: p38 phosphorylation in medullary microglia mediates ectopic orofacial inflammatory pain in rats

Fig. 2

Microglial activation in Vc following CFA injection into trapezius muscle. a Photomicrograph of Iba1-IR cells in Vc on day 4 after the CFA injection. High-magnificated photomicrograph of Iba1-IR cells in Vc on day 4 after CFA (b) or saline (c) injection. d High-magnificated photogmicrograph of Iba1-IR cells in Vc on day 15 after CFA injection. Scale bar 500 μm (a); 100 μm (b–d). e Density of the Iba1 immuno-products in Vc (1,440, 2,160 and 2,800 μm caudal to the obex) on day 4 and 15 after saline or CFA injection. Data represent mean ± SEM; n = 13–14 in each; *p < 0.05, **p < 0.01; compared to saline-injected rats by Student’s t tests.

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