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Fig. 4 | Molecular Pain

Fig. 4

From: Pirt contributes to uterine contraction-induced pain in mice

Fig. 4

The neurochemical properties of Dil-labeled DRG neurons. ac Dil-labeled cells did not colocalize with NF-200. Dil-labeled cells and NF-200-expressing cells are indicated by white and yellow arrows, respectively. Dil-labeled DRG neurons colocalized with IB4 (df) and Pirt (gi). jl DRG section including Pirt-positive and Dil-labeled neurons was immunostained by TRPV1. m A merged image of Dil-labeled, Pirt-positive and TRPV1-staining neurons. The white arrows designate double-labeled cells. Pirt expression was assessed by fluorescence microscopy in Pirt−/− mice, in which the entire Pirt-coding region has been replaced with an EGFPf-IRESrtTA-ACN-targeting construct. Scale bar 20 µm

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