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Fig. 3 | Molecular Pain

Fig. 3

From: Small-conductance calcium-activated potassium (SK) channels in the amygdala mediate pain-inhibiting effects of clinically available riluzole in a rat model of arthritis pain

Fig. 3

Inhibitory effects of riluzole administered into the amygdala (CeA) in arthritic rats. Stereotaxic administration of riluzole (1 mM, concentration in the microdialysis probe, 15 min) into the CeA of arthritic rats (n = 8 rats; 5 h postinduction) significantly inhibited audible (a) and ultrasonic (b) vocalizations evoked by noxious stimulation of the knee joint compared to predrug values. Bar histograms show mean ± SEM. *,**P < 0.05, 0.01; paired t test

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Molecular Pain

ISSN: 1744-8069

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