Skip to main content
Fig. 6 | Molecular Pain

Fig. 6

From: Leukotriene enhances NMDA-induced inward currents in dorsal horn neurons of the rat spinal cord after peripheral nerve injury

Fig. 6

A selective BLT1 antagonist inhibited LTB4-induced enhancement of NMDA currents. a Enhancement of NMDA-currents by LTB4 was significantly inhibited in the presence of the selective BLT1 antagonist, U75302 (20 μM). b Bar graph showing the average increase rate of NMDA-induced inward currents by NMDA alone as control (open bar) and under the treatment with LTB4 (black bar) and in the presence LTB4 during application U75302 (gray bar), (n = 5). c U75302 had no effect on NMDA-induced currents (n = 9). d Bar graph showing the average increase rate of NMDA-induced inward currents by NMDA alone as control (open bar) and under the treatment with U75302 (black bar).  *, P < 0.05

Back to article page