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Fig. 3 | Molecular Pain

Fig. 3

From: Limited changes in spinal lamina I dorsal horn neurons following the cytotoxic ablation of non-peptidergic C-fibers

Fig. 3

Quantitative analysis of the density of IB4-binding (a) and CGRP-ir (b) varicosities per area unit (µm2) in the sciatic territory, 21 days after injection in the sciatic nerve of IB4-saporin (IB4-SAP, N = 5) or saline (sham, N = 4), in the ipsilateral dorsal horn. a Ipsilateral to IB4-saporin injection the number of IB4-positive varicosities was reduced (IB4-SAP) compared to sham animals (Student’s t-test; *P < 0.02). b Ipsilateral to IB4-saporin injection, the density of CGRP ir varicosities was slightly reduced, but the difference from sham was not significant (Student’s t-test)

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