Fig. 2
From: Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons
Expression of Nav1.6 and Navβ4 in DRG neurons. Examples of immunocytochemical staining of Navβ4 and Nav1.6 in primary cultured DRG neurons are shown in a and b. Navβ4 signal is shown in green and Nav1.6 signal is shown in red with corresponding brightfield (DIC) image shown in c. Merged image (d) shows that some DRG neurons but not all express both Nav1.6 and Navβ4. e Strong co-expression of Nav1.6 and Navβ4 signal is mainly observed in medium-large diameter neurons (>400 um2, n = 344), but not small diameter neurons (<400 um2, n = 347) as indicated by the Pearson correlation coefficient. Asterisks (****) represent p < 0.0001 obtained from student’s t test. Scale bar 50 μm