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Fig. 3 | Molecular Pain

Fig. 3

From: Navβ4 regulates fast resurgent sodium currents and excitability in sensory neurons

Fig. 3

In vivo knockdown decreases Navβ4 expression levels. Representative images of immunocytochemical staining of Navβ4 in primary cultured DRG neurons from rats injected with non-targeting siRNA (n.t. control, a) or Navβ4 siRNA (β4siRNA, b) 72 h post injection. c Corrected total cell fluorescence (CTCF) is significantly decreased in DRG neurons from rats injected with β4siRNA (n = 352 from three rats, p < 0.0001) compared with n.t. control (n = 264 from three rats). Scale bar 50 μm. Asterisks (****) represent p < 0.0001 obtained from student’s t test

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