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Fig. 2 | Molecular Pain

Fig. 2

From: Transient, activity dependent inhibition of transmitter release from low threshold afferents mediated by GABAA receptors in spinal cord lamina III/IV

Fig. 2

Gabazine enhances the second eEPSC peak in a train of four pulses. a Percentage changes of the eEPSC mean peak amplitudes (determined by averaging five traces in control and five traces in gabazine) in a sample of 17 lamina III/IV neurons (same experiment illustrated in Fig. 1). Cells numbered 1–10 showed a significant effect of gabazine on the second peak. b Mean values of percentage changes for each peak in the 17 neuron sample. c Mean absolute peak amplitudes in control and gabazine: the antagonist produces a significant increase only in the second eEPSC peak (paired t test, p = 0.013, n = 17)

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