Fig. 1
From: The effect of kinin B1 receptor on chronic itching sensitization
Scratching behaviors in 30 min of DCP-treated mice. Test substances were administered 30 min before observation. Graph showing increased spontaneous scratching of animal model in DCP-treated group (a). Preventive treatment with B1R antagonist R892 (b), kallikrein inhibitor NFM (c) significantly suppressed spontaneous scratching compared with sham-treated group (n = 8), and was significantly different from the vehicle group, while B2R antagonist HOE-140 (d) did not. *P < 0.05 as determined by the Student t test