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Table 2 Regions that show connectivity change with pre-acupuncture resting state network after longitudinal acupuncture treatment (pre-treatment 6—pre-treatment 1) comparing acupuncture to sham group

From: The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients

Network

Group

Area

Z score

Peak coordinate (x, y, z)

Right frontoparietal network

Acu > Sham

rACC/MPFC

4.45

12, 36, −12

Right parahippocampus

3.58

32, 0, −18

Right midinsula/precentralgyrus

3.98

52, −2, 2

Right sup temporal/right inf temporal gyrus

4.15

38, 4, −34

Right inferior frontal/mid frontal gyrus

3.25

50, 32, −4

Left midinsula

4

−24, 4, 6

Left thalamus

3.77

−22, −18, 10

Left claustrum/parahippocampus

3.4

−38, −12, −14

Left sup temporal gyrus

3.46

−50, −6, 0

Sham > Acu

None

Executive control network

Acu > Sham

rACC

3.95

4, 32, 2

Left MPFC

3.4

−16, 56, −8

Left insula

3.72

−46, 2, 2

Left inferior frontal gyrus

3.33

−42, 36, 6

Sham > Acu

None

Somatosensory network

Acu > Sham

None

Sham > Acu

Dorsal ACC

4.74

−8, 18, 38

Bilateral sup frontal/left middle frontal/medial frontal gyrus

3.6

−20, 48, 42