Fig. 3
From: Impairments of the primary afferent nerves in a rat model of diabetic visceral hyposensitivity
The mechanosensitivity of the pelvic afferent nerves in the ex vivo rat colorectum preparations. a and b show representative recording of multiunit afferent activity during ramp distension of the colorectum. From top to bottom are traces of the pressure, raw (multiunit) neurogram, the multiunit discharge frequency and the discharge rate of low threshold (LT), wide dynamic range(WDR) and high threshold(HT) units discriminated through principal component analysis. c shows the averaged pressure-response curves of multiunits (n = 17 and 23), LT (n = 6 and 9), WDR (n = 22 and 22) and HT units (n = 3 and 6) of the control and diabetic groups.*P < 0.05; **P < 0.01, un-paired t test of AUC